鍩哄洜鍚嶏細

Prr27

浜у搧鍒悕锛欬p style="text-indent: 2em;">4930432K09Rik锛 Prr27锛 proline rich 27锛 proline rich 27锛 proline-rich protein 27锛 4鍙锋煋鑹蹭綋寮€鏀鹃槄璇绘40锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. The C4orf40 gene product has been provisionally designated C4orf40 pending further characterization.