鍩哄洜鍚嶏細

Cfap418

浜у搧鍒悕锛欬p style="text-indent: 2em;">2610301B20Rik锛 AI428449锛 Cfap418锛 cilia and flagella associated protein 418锛 cilia and flagella associated protein 418锛 cilia- and flagella-associated protein 418锛 protein C8orf37 homolog锛 8鍙锋煋鑹蹭綋寮€鏀鹃槄璇绘37锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf37 gene product has been provisionally designated C8orf37 pending further characterization.