靶标：
PLEKHG6
半岛bd体育手机客户端 别名：
MyoGEF； PLEKHG6； pleckstrin homology and RhoGEF domain containing G6； pleckstrin homology and RhoGEF domain containing G6； pleckstrin homology domain-containing family G member 6； PH domain-containing family G member 6； myosin II interacting GEF； myosin interacting guanine nucleotide exchange factor； pleckstrin homology domain containing, family G (with RhoGef domain) member 6； 肌球蛋白相互作用G蛋白交换因子；
背景信息：
PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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