靶标:
UBE4B
半岛bd体育手机客户端 别名:
E4; HDNB1; UBOX3; UFD2; UFD2A; UBE4B; ubiquitination factor E4B; ubiquitination factor E4B; ubiquitin conjugation factor E4 B; RING-type E3 ubiquitin transferase E4 B; homologous to yeast UFD2; homozygously deleted in neuroblastoma-1; ubiquitin-fusion degradation protein 2; ubiquitination factor E4B (UFD2 homolog, yeast);
背景信息:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。