靶标:
RAPGEF5
半岛bd体育手机客户端 别名:
GFR; MR-GEF; MRGEF; REPAC; RAPGEF5; Rap guanine nucleotide exchange factor 5; Rap guanine nucleotide exchange factor 5; rap guanine nucleotide exchange factor 5; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; Rap guanine nucleotide exchange factor (GEF) 5; guanine nucleotide exchange factor for Rap1; related to Epac; Rap鸟嘌呤核苷酸交换因子(GEF)5;
背景信息:
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008],
宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。