靶标:
MAP3K12
半岛bd体育手机客户端 别名:
DLK; HP09298; MEKK12; MUK; ZPK; ZPKP1; MAP3K12; mitogen-activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 12; MAPK-upstream kinase; dual leucine zipper bearing kinase; dual leucine zipper kinase DLK; leucine zipper protein kinase; mixed lineage kinase; protein kinase MUK; 双亮氨酸拉链激酶DLK;
背景信息:
This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010],
宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。