Brodimoprim (Ro 10-5970), 是一种甲氧苄啶类似物,是一种口服活性二氢叶酸还原酶 (dihydrofolate reductase) 抑制剂。Brodimoprim 对广谱革兰氏阴性和革兰氏阳性细菌具有高度活性。
货号:ajcx36038
CAS:56518-41-3
分子式:C13H15BrN4O2
分子量:339.19
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
Brodimoprim (Ro 10-5970), a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria[1].
[1]. Weidekamm E. Pharmacokinetics of brodimoprim. J Chemother. 1993;5(6):475-479.
[2]. Marchese A, et al. Brodimoprim: effects of subminimal inhibitory concentrations on virulence traits of respiratory and urinary tract pathogens, and on plasmid transfer and stability. J Chemother. 1996;8(3):171-177.