An internal standard for the quantification of difloxacin
货号:ajcx22278
CAS:1173147-93-7
分子式:C21H16D3F2N3O3
分子量：402.4
溶解度:Chloroform: soluble,Ethanol: soluble
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Difloxacin-d₃is intended for use as an internal standard for the quantification of difloxacin by GC- or LC-MS. Difloxacin is a fluoroquinolone antibiotic.¹It is active against isolates of anaerobic bacteria, includingB. fragilis, as well asFusobacteriumandActinomycesspecies with MIC values ranging from ≤0.125 to 8 ?g/ml. It eliminatesE. coliandB. fragilisinfection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.²

1.Bansal, M.B., and Thadepalli, H.Activity of difloxacin (A-56619) and A-56620 against clinical anaerobic bacteria in vitroAntimicrob. Agents Chemother.31(4)619-621(1987) 2.Thadepalli, H., Gollapudi, S.V., and Chuah, S.K.Therapeutic evaluation of difloxacin (A-56619) and A-56620 for experimentally induced Bacteroides fragilis-associated intra-abdominal abscessAntimicrob. Agents Chemother.30(4)574-576(1986)