Tenofovir amibufenamide (HS-10234) 是一种 Tenofovir 前药,是一种具有口服活性的抗病毒剂。Tenofovir amibufenamide 抑制乙型肝炎病毒 (HBV),可用于慢性乙型肝炎 (CHB) 研究。
货号:ajcx38554
CAS:1571076-26-0
分子式:C22H31N6O5P
分子量:490.49
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
Tenofovir amibufenamide (HS-10234), a Tenofovir prodrug, is an orally active antiviral agent. Tenofovir amibufenamide inhibits HBV, and can be used for chronic hepatitis B (CHB) study[1][2].
[1]. Zhihong Liu, et al. Randomised clinical trial: 48 weeks of treatment with tenofovir amibufenamide versus tenofovir disoproxil fumarate for patients with chronic hepatitis B. Aliment Pharmacol Ther. 2021 Nov;54(9):1134-1149.
[2]. Hong Zhang, et al. Randomised clinical trial: safety, efficacy and pharmacokinetics of HS-10234 versus tenofovir for the treatment of chronic hepatitis B infection. Aliment Pharmacol Ther. 2021 Jan;53(2):243-252.