LRRK2 inhibitor 1 是有效，选择性的 LRRK2 抑制剂，IC50 为 6.8。
货号:ajcx39486
CAS:1802525-61-6
分子式:C20H23N5O4
分子量：397.43
溶解度:DMSO : 62.5 mg/mL (157.26 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

LRRK2 inhibitor 1 is a potent, selective and oral LRRK2 inhibitor with an pIC50 of 6.8.

[1]. Ding X, et al. Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors. Bioorg Med Chem Lett. 2018 May 15;28(9):1615-1620.