(±)-Leucine-d10 (DL-Leucine-d10) 是 (±)-Leucine 的氘代物。(±)-Leucine (DL-Leucine)，亮氨酸的异构体，是一种化学杀菌剂和膳食添加剂。(±)-Leucine 抑制大肠杆菌的生长达92.08%。
货号:ajcx39894
CAS:29909-01-1
分子式:C6H3D10NO2
分子量：141.23
溶解度:H2O : 12.5 mg/mL (88.51 mM; ultrasonic and warming and heat to 80°C)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

(±)-Leucine-d10 (DL-Leucine-d10) is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hendricks DE, et, al. Attractiveness of tobacco budworm females altered by oral chemosterilants and dietary additives. Journal of Chemical Ecology. 1977 Mar; 127-131.