Secretin is an endogenous 27-amino acid gastrointestinal hormone and neuropeptide that regulates secretion from the stomach, pancreas, and liver.
货号:ajcx18974
CAS:N/A
分子式:C130H220N44O40?XCF3COOH
分子量：3039.4
溶解度:Water: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Secretin is an endogenous 27-amino acid gastrointestinal hormone and neuropeptide that regulates secretion from the stomach, pancreas, and liver. It belongs to the secretin/glucagon superfamily of peptides, which includes glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . Secretin dose-dependently increases somatostatin release from primary human antral cells in vitro. In vivo, secretin dose-dependently increases the volume of pancreatic secretion as well as inhibits gastric acid secretion induced by gastrin I in rats when administered at a dose of 100 pmol/kg per h. Secretin (40 μg/kg, i.v.) increases the number of neurons expressing c-fos in the central amygdala and area postrema in rats.