A mycotoxin and AChE inhibitor
货号:ajcx20780
CAS:70407-19-1
分子式:C28H30O9
分子量：510.5
溶解度:DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Territrem A is a mycotoxin originally isolated from A. terreus that irreversibly inhibits acetylcholinesterase (AChE; IC50 = 24 nM for the electric eel enzyme).1 It is toxic to mice, inducing tremors with a median tremulous dose of 0.31 mg/kg, and has an LD50 value of 17.6 mg/kg.2

|1. Chen, J.-W., and Ling, K.-H. Territrems: Naturally occurring specific irreversible inhibitors of acetylcholinesterase. J. Biomed. Sci. 3(1), 54-58 (1996).|2. Ling, K.H., Liou, H.-H., Yang, C.-M., et al. Isolation, chemical structure, acute toxicity, and some physicochemical properties of territrem C from Aspergillus terreus. Appl. Environ. Microbiol. 47(1), 98-100 (1984).