A derivative of betulin
货号:ajcx24130
CAS:27570-20-3
分子式:C32H52O3
分子量:484.8
溶解度:DMF: 5 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
3-Acetyl betulin is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1,2It is an intermediate in the synthesis of various lupane and germanicane triterpenes and saponins with anticancer activity.
1.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007) 2.B?benek, E., Kadela-Tomanek, M., Chrobak, E., et al.Novel triazoles of 3-acetylbetulin and betulone as anticancer agentsMed. Chem. Res.27(9)2051-2061(2018)