An active metabolite of chlorpromazine
货号:ajcx24408
CAS:51938-11-5
分子式:C17H19ClN2OS?HCl
分子量：371.3
溶解度:Methanol: slightly soluble
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

7-hydroxy Chlorpromazine is an active metabolite of the typical antipsychotic chlorpromazine .¹In vivo, 7-hydroxy chlorpromazine (5 mg/kg) increases plasma prolactin levels in male rats. It also reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats when administered at a dose of 1.6 mg/kg.²

1.Meltzer, H.Y., Fang, V.S., Simonovich, M., et al.Effect of metabolites of chlorpromazine on plasma prolactin levels in male ratsEur. J. Pharmacol.41(4)431-436(1977) 2.Bunney, B.S., and Aghajanian, G.K.A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neuronsLife Sci.15(2)309-318(1974)