m-PEG5-NHSester是一种基于PEG的PROTAClinker，可用于PROTAC的合成。
货号:ajcx31106
CAS:874208-94-3
分子式:C16H27NO9
分子量：377.39
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.