Nangibotide TFA 是一种 TREM-1 受体抑制剂,可调节先天免疫反应。Nangibotide TFA 可以减少啮齿动物心肌缺血再灌注模型中的全身和原位炎症反应。
货号:ajcx36676
CAS:N/A
分子式:C56H83F3N14O24S2
分子量:1457.46
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
Nangibotide TFA is a TREM-1 receptor inhibitor that can modulate innate immune response. Nangibotide TFA can reduce systemic and in situ inflammatory reaction in rodent models of myocardial ischaemia-reperfusion[1].
[1]. Cuvier V, et, al. A first-in-man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM-1 receptor inhibition. Br J Clin Pharmacol. 2018 Oct;84(10):2270-2279.