FTI-276是有效的proteinfarnesyltransferase(PFT)抑制剂,作用于恶性疟原虫和人类的IC50值分别为0.9和0.5nM。
货号:ajcx13026
CAS:170006-72-1
分子式:C21H27N3O3S2
分子量：433.59
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human.

[1]. Chakrabarti D, et al. Protein farnesyltransferase and protein prenylation in Plasmodium falciparum.J Biol Chem. 2002 Nov 1; 277(44):42066-73. Epub 2002 Aug 22.