Worenine 分离自黄连。Worenine 在大鼠体内第一阶段代谢中显示出脱氢，氢化，羟基化和脱亚甲基反应。在大鼠体内 II 期代谢中主要为为硫酸化和葡萄糖醛酸化反应。
货号:ajcx15926
CAS:38763-29-0
分子式:C20H16NO4
分子量：334.34
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Worenine is isolated from Coptis chinensis. Worenine in rat shows dehydrogenization, hydrogenation, hydroxylation, and demethylene reactions in phase I metabolism. The phase II metabolism sulfation and glucuronidation reactions[1].

[1]. Chen H, et al. Characterization of metabolites of worenine in rat biological samples using liquid chromatography-tandem mass spectrometry.J Pharm Biomed Anal. 2010 Jan 5;51(1):236-43.