DBCO-PEG4-acetic-Val-Cit-PAB是一种可降解(cleavable)的含4个单元PEG的ADClinker,可用于合成抗体偶联药物(ADC)。
货号:ajcx30468
CAS:N/A
分子式:C45H57N7O10
分子量:855.97
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.