DL-Laudanosine 是 Atracurium 和 Cisatracurium 的代谢物，可透过血脑屏障，引起兴奋和癫痫发作。
货号:ajcx32600
CAS:1699-51-0
分子式:C21H27NO4
分子量：357.44
溶解度:DMSO : 100 mg/mL (279.77 mM)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood-brain barrier and may cause excitement and seizure activity[1].

DL-Laudanosine (Laudanosine) appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals and it is reported to cause arousal from anaesthesia in subconvulsive doses[1].

参考文献:
[1]. V Fodale, et al. Laudanosine, an Atracurium and Cisatracurium Metabolite. Eur J Anaesthesiol. 2002 Jul;19(7):466-73.
[2]. D J Chapple, et al. Cardiovascular and Neurological Effects of Laudanosine. Studies in Mice and Rats, and in Conscious and Anaesthetized Dogs. Br J Anaesth. 1987 Feb;59(2):218-25.