Vonafexor (EYP001) 是一种 FXR 激动剂，具有抗 HBV 的作用。
货号:ajcx17372
CAS:1192171-69-9
分子式:C19H15Cl3N2O5S
分子量：489.76
溶解度:DMSO: 83.33 mg/mL (170.14 mM)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Vonafexor (EYP001) is a selective FXR agonist anti-HBV effects[1][2].

[1]. Joly S, et al. The selective FXR agonist EYP001 is well tolerated in healthy subjects and has additive anti-HBV effect with nucleoside analogues in HepaRG cells. J Hepatol 66(1):S690. [2]. Fiorucci S,et al. Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH) [published online ahead of print, 2020 Jun 19]. Expert Opin Investig Drugs. 2020;1-10.