PGE2 is the major eicosanoid product of cyclooxygenase-1 and 2 in epithelial cells, leukocytes, reproductive tissues, and many others.
货号:ajcx18888
CAS:N/A
分子式:C54H96N4O17S
分子量:1105.4
溶解度:DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
PGE2 is the major eicosanoid product of cyclooxygenase-1 and 2 in epithelial cells, leukocytes, reproductive tissues, and many others. PGE2 contracts smooth muscle, protects the gastric mucosa, modulates immune function, and regulates fertility and implantation. PGE2 acts through at least four G-protein coupled receptors, EP1-EP4. PGE2-PEG11-biotin is an affinity probe which allows PGE2 to be detected or immobilized using the biotin ligand. The PEG11 moiety serves to separate the biotin linker from PGE2 with a hydrophilic spacer. It is thus a tool to be used in the elucidation of PGE2 actions or interactions in aqueous solutions.