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Fosinopril-d7(sodium salt)
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fosinopril-d7(sodium salt)图片
包装: 1mg
规格: 98%
市场价: 5408元
分子量: 592.7

半岛bd体育手机客户端 介绍
An internal standard for the quantification of fosinopril
货号:ajcx22524
CAS:1217819-83-4
分子式:C30H38D7NO7P.Na
分子量:592.7
溶解度:Acetonitrile:Methanol (1:1): Soluble,DMSO: Soluble,Water: Soluble
纯度:98%
存储:Store at -20°C
库存: 现货

Background:

Fosinopril-d7is intended for use as an internal standard for the quantification of fosinopril by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor fosinoprilat.1Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 ?mol/kg, respectively. Fosinopril (2.5 mg/kg) reduces fractional shortening and decreases left ventricular size in a porcine model of congestive heart failure.2Formulations containing fosinopril have been used in the treatment of hypertension and congestive heart failure.


1.DeForrest, J.M., Waldron, T.L., Harvey, C., et al.Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: In vitro and preclinical in vivo pharmacologyJ. Cardiovasc. Pharmacol.14(5)730-736(1989) 2.McElmurray, J.H., III, Mukherjee, R., New, R.B., et al.Angiotensin-converting enzyme and matrix metalloproteinase inhibition with developing heart failure: Comparative effects on left ventricular function and geometryJ. Pharmacol. Exp. Ther.291(2)799-811(1999)

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