MDM2-IN-1 (Compound 30) 是一种合成的 MDM2-p53 相互作用 (MDM2) 抑制剂，包含反式 (D-)构型。
货号:ajcx33958
CAS:1410737-09-5
分子式:C23H21Cl2FN2O3
分子量：463.33
溶解度:DMSO : 22.5 mg/mL (48.56 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration[1].

[1]. Aguilar A, et al. Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles. J Med Chem. 2014 Dec 26;57(24):10486-98.