[18F]AZD4694 Precursor 是合成 [18F] AZD4694的前体,用于合成 [18F] AZD4694。[18F] AZD4694 是一种淀粉样蛋白 -β 成像配体,对淀粉样蛋白 -β 斑块具有高亲和性。
货号:ajcx34346
CAS:1211333-20-8
分子式:C22H25N3O7
分子量:443.45
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
[18F]AZD4694 Precursor is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques[1].
18F-AZD4694 is an amyloid-β imaging ligand with high affinity for amyloid-β plaques. 18F-AZD4694 is a high affinity (Kd= 2.3 nM) radioligand for imaging amyloid-β plaques that displays lower white matter binding compared to other fluorinated amyloid-PET tracers, enabling easier visual reads[1].
[1]. Therriault J, et al. Determining Amyloid-β Positivity Using 18F-AZD4694 PET Imaging. J Nucl Med. 2021;62(2):247-252.