Ro19-4603 is a benzodiazepine inverse agonist. Ro19-4603 binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABAA receptors (Kis are ~ 0.2 and ~ 2.6 nM for DS and DI receptors respectively). References: June HL, Torres L, Cason CR, Hwang BH, Braun MR, Murphy JM. The novel benzodiazepine inverse agonist RO19-4603 antagonizes ethanol motivated behaviors: neuropharmacological studies. Brain Res. 1998 Feb 16;784(1-2):256-75. PubMed PMID: 9518641.

纯度：≥98%

CAS：99632-94-7