Amino-PEG5-CH2COOH 是一种 PROTAC linker，属于 PEG 类。NH2-PEG5-CH2COOH 可用于合成PROTAC分子。
货号:ajcx35566
CAS:141282-35-1
分子式:C12H25NO7
分子量：295.33
溶解度:DMSO : 20 mg/mL (67.72 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.