Lupeolacetate是Lupeol的衍生物，通过下调TNF-α、IL-1β、MCP-1、COX-2、VEGF和granzymeB来抑制类风湿关节炎的进展。
货号:ajcx29474
CAS:1617-68-1
分子式:C32H52O2
分子量：468.75
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].

[1]. Wang WH, et al. Lupeol acetate ameliorates collagen-induced arthritis and osteoclastogenesis of mice through improvement of microenvironment. Biomed Pharmacother. 2016;79:231-240.