S-(1-Hydroxy-2-methylpropan-2-yl)methanesulfonothioate是一种谷胱甘肽可降解(cleavable)的ADClinker，用于抗体偶联药物(ADCs)，属于Alkyl-Chain类，是ADCs用于mAb附着的连接体部分。
货号:ajcx31430
CAS:2127875-65-2
分子式:C5H12O3S2
分子量：184.28
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].

[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.