LSD1/HDAC6-IN-1 是一种具有口服活性的组蛋白去甲基化酶 LSD1 和组蛋白去乙酰酶 HDAC6 (LSD1/HDAC6) 双重抑制剂，具有抗肿瘤活性。LSD1/HDAC6-IN-1 可用于多发性骨髓瘤 (MM) 的研究。
货号:ajcx33714
CAS:N/A
分子式:C25H33N3O2
分子量：407.55
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

LSD1/HDAC6-IN-1 is an orally active dual inhibitor of lysine specific demethylase 1(LSD1)/Histone deacetylase 6 (HDAC6), with anti-tumor activity. LSD1/HDAC6-IN-1 can be used for the research of multiple myeloma (MM)[1].

LSD1/HDAC6-IN-1 shows superior potency in multiple MM lines[1].

LSD1/HDAC6-IN-1 is efficacy in the MM.1S xenograft model[1].

[1]. M Naveen Sadhu, et al. Novel dual LSD1/HDAC6 inhibitors for the treatment of multiple myeloma. Bioorg Med Chem Lett. 2020 Dec 24;34:127763.