IRAK-4 protein kinase inhibitor 2 (compound 1) 是一种有效的白介素 1 (IL-1) 受体相关激酶 4 (IRAK-4) 抑制剂，IC50 值为 4 μM。IRAK-4 protein kinase inhibitor 2 可用于研究与炎症和免疫相关的疾病。
货号:ajcx34010
CAS:301675-24-1
分子式:C14H10N4O3
分子量：282.25
溶解度:DMSO : 10 mg/mL (35.43 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

IRAK-4 protein kinase inhibitor 2 (compound 1) is a potent inhibitor of interleukin-1 (IL-1) receptor-associated kinase-4 (IRAK-4), with an IC50 of 4 μM. IRAK-4 protein kinase inhibitor 2 can be used for the research of inflammatory and immune-related conditions or disorders[1].

IRAK-4 protein kinase inhibitor 2 (compound 1) also inhibits IRAK-1, with an IC50 of<10 μM[1].

[1]. Powers JP, et, al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.