C56H85N17O11?XCF3COOH
货号:ajcx23854
CAS:N/A
分子式:C56H85N17O11?XCF3COOH
分子量：1172.4
溶解度:Water: 2 mg/ml
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Kinetensin is a nonapeptide that has been found in pepsin-treated human plasma.¹It binds to neurotensin receptors in HT-29 cells and mouse brain (K_is = 1,396 and 149.6 nM, respectively, in radioligand binding assays) but does not induce the accumulation of intracellular calcium in HT-29 cells (EC₅₀= >10,000 nM).²It induces histamine release in isolated rat peritoneal mast cells with an EC₅₀value of approximately 10 ?M.³Intradermal administration of kinetensin induces vascular permeability in rats.

1.Mogard, M.H., Kobayashi, R., Chen, C.F., et al.The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: Homology with human serum albumin, neurotensin and angiotensinBiochem. Biophys. Res. Commun.136(3)983-988(1986) 2.Akunne, H.C., Demattos, S.B., Whetzel, S.Z., et al.Agonist properties of a stable hexapeptide analog of neurotensin, NαMeArg-Lys-Pro-Trp-tLeu-Leu (NT1)Biochem. Pharmacol.49(8)1147-1154(1995) 3.Sydbom, A., Ware, J., and Mogard, M.H.Stimulation of histamine release by the peptide kinetensinAgents Actions27(1-2)68-71(1989)