Control peptide version of dynamin inhibitory peptide, myristoylated
货号:ajcx26780
CAS:N/A
分子式:C61H107N19O14
分子量:1330.64
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibitory peptide, has no significant effect on GABAA receptor-mediated miniature IPSPs. Active Analog also available.
Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419 PMID:9148966 |Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID:11050117 |Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302 PMID:12646920