(2R/S)-6-PNG (6-Prenylnaringenin) 是一种有效且可逆的 Cav3.2 T 型 Ca2+ 通道 (T-channels) 阻滞剂。
货号:ajcx27750
CAS:68682-01-9
分子式:C20H20O5
分子量:340.37
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
Cav3.2 (T-type) Ca2+ channel blocker (IC50 = 991 nM). Suppresses neuropathic allodynia in mouse pain models.
Sekiguchi et al (2018) Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice. Neuropharmacology 138 232 PMID:29913186