KI-7 是一种 A2B 腺苷受体正变构调节剂。
货号:ajcx27816
CAS:1489263-00-4
分子式:C23H18N2O2
分子量：354.4
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Adenosine A2B receptor positive allosteric modulator. Potentiates the NECA -induced increase in cAMP production in CHO cells expressing A2B receptors. Also potentiates the effects of NECA and the A2B receptor agonist BAY 60-6583 in mediating osteoblast differentiation from MSCs in vitro.

Trincavelli et al (2014) Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. Biochim.Biophys.Acta 1843 2957 PMID:25241343 |Trincavelli et al (2014) Allosteric modulators of human A2B adenosine receptor. Biochim.Biophys.Acta 1840 1194 PMID:24361612