C58H65F2N7O11S
货号:ajcx28178
CAS:2230821-68-6
分子式:C58H65F2N7O11S
分子量：1106.25
溶解度:DMSO|55.31|50|
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089; ) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells.