Sandacanol是嗅觉受体(OR10H1)的特异性激动剂。Sandacanol诱导膀胱癌细胞发生细胞周期停滞和凋亡(apoptosis)。
货号:ajcx31444
CAS:28219-61-6
分子式:C14H24O
分子量：208.34
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Sandacanol is a specific agonist of olfactory receptor (OR10H1). Sandacanol induces cell cycle arrest and some apoptosis in bladder cancer cells[1].

Sandacanol (50, 100, 300, 500, and 700 μM; 24 or 48 h) treatment significantly diminishes cell viability, cell proliferation and migration and induces a limited degree of apoptosis in BFTC905 bladder cancer cells[1].

[1]. Lea Weber, et al. Characterization of the Olfactory Receptor OR10H1 in Human Urinary Bladder Cancer. Front Physiol. 2018 May 16;9:456.