MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH 是一种可降解 (cleavable) 的 ADC linker,用于合成可用于合成抗体偶联药物 (ADC)。
货号:ajcx33378
CAS:1599440-25-1
分子式:C28H36N6O10
分子量:616.62
溶解度:DMSO : 120 mg/mL (194.61 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Masuda, Takeshi, et al. Conjugu? anticorps-m?dicament. WO2014057687A1.