Mal-PEG1-acid是一种不可降解 (non-cleavable) 的含 1 个单元 PEG 的 ADC linker,可用于合成 抗体偶联药物 (ADC)。
货号:ajcx29486
CAS:760952-64-5
分子式:C9H11NO5
分子量:213.19
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Karpov AS, et al. Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody-Drug Conjugates. ACS Med Chem Lett. 2018 Jun 28;9(8):838-842.