(2R,5S)-Ritlecitinib (2R,5S)-PF-06651600) 是一种有效的选择性的 JAK3 抑制剂 (IC50=144.8 nM)。详细信息请参考专利US20150158864A1，example 68。
货号:ajcx33112
CAS:1792180-79-0
分子式:C15H19N5O
分子量：285.34
溶解度:DMSO : 220 mg/mL (771.01 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective JAK3 inhibitor (IC50=144.8 nM) extracted from patent US20150158864A1, example 68[1].

[1]. Atli Thorarensen, et al. Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyr-rolo[2,3-d]pyridinyl acrylamides. US20150158864A1.