Calcitonin gene-related protein (CGRP) is a neuropeptide and a product of alternative splicing of the calcitonin gene.
货号:ajcx19080
CAS:N/A
分子式:C139H230N44O38?XCF3COOH
分子量：3125.6
溶解度:Water: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Calcitonin gene-related protein (CGRP) is a neuropeptide and a product of alternative splicing of the calcitonin gene. It induces vasodilation of both arteries and veins in addition to various non-vascular biological activities. α-CGRP (8-37) is an antagonist of CGRP receptors (IC50 = 4.9 nM in SK-N-MC cells expressing the human receptor) that inhibits CGRP-induced vasodilation. In a mouse model of headache, α-CGRP (8-37) application to the dura mater reduces behavior induced by application of capsaicin and inflammatory mediators. α-CGRP (8-37) (human) is a peptide fragment derived from the human CGRP protein sequence.