| 包装: | 1mg |
| 规格: | 98% |
| 市场价: | 4815元 |
| 分子量: | 412 |
Background:
Toremifene-d6is intended for use as an internal standard for the quantification of toremifene by GC- or LC-MS. Toremifene is an orally bioavailable selective estrogen receptor modulator (SERM) that evokes tissue-dependent effects similar to that of tamoxifen .1It has been shown to block estrogen-stimulated growth of MCF-7 breast cancer cells grown in tissue culture, to inhibit ovariectomy-induced bone loss in rats, and to stimulate endometrial growth similar to that of tamoxifen.1
1.Goldstein, S.R., Siddhanti, S., Ciaccia, A.V., et al.A pharmacological review of selective oestrogen receptor modulatorsHum. Reprod. Update6(3)212-224(2000)
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