3-Azidopropionic Acid Sulfo-NHS ester 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
货号:ajcx29060
CAS:2055198-09-7
分子式:C7H7N4NaO7S
分子量:314.21
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
3-Azidopropionic Acid Sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.