BCN-PEG4-acid是一种可降解(cleavable)的含4个单元PEG的ADClinker,可用于合成抗体偶联药物(ADC)。
货号:ajcx30244
CAS:1881221-47-1
分子式:C22H35NO8
分子量:441.52
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.