Harmalolhydrochloride是一种β-咔啉生物碱，存在于几种药用植物中，如Peganumharmala。Harmalolhydrochloride,Harmaline的主要代谢产物，在转录和翻译后水平上显著抑制二恶英介导的CYP1A1诱导。Harmalolhydrochloride具有抗氧化和清除羟自由基的特性。
货号:ajcx30756
CAS:6028-07-5
分子式:C12H13ClN2O
分子量：236.7
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties[1].

[1]. El Gendy MA, et al. Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food Chem Toxicol. 2012;50(2):353-362.