Propargyl-PEG4-5-nitrophenyl carbonate is a PEG analogue containing a propargyl group and nitrophenyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. NPC is reactive towards the amino group of lysine by means of stable urethane linkages. PEG Linkers may be useful in the development of antibody drug conjugates. References: Sano K, Nakajima T, Miyazaki K, Ohuchi Y, Ikegami T, Choyke PL, Kobayashi H. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. doi: 10.1021/bc400050k. Epub 2013 May 3. PubMed PMID: 23600922; PubMed Central PMCID: PMC3674550.

纯度：≥98%

CAS：1422540-81-5