DBCO-C6-acid 是一种不可降解 (non-cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs) 的合成。DBCO-C6-acid 可用于合成 carmaphycin 类似物。
货号:ajcx32618
CAS:1425485-72-8
分子式:C21H19NO3
分子量：333.38
溶解度:DMSO : 100 mg/mL (299.96 mM)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

参考文献:
[1]. Almaliti J, et al. Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.