PI 3-kinase δ inhibitor
货号:ajcx27258
CAS:1879887-94-1
分子式:C22H18N2O3
分子量:358.39
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
PI 3-kinase δ inhibitor (IC50 values are 0.64 and 5.0 μM for PI-3Kδ and PI3Kβ, respectively). Exhibits anticancer activity in a renal cancer cell line.
Morrison et al (2016) Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur.J.Med.Chem. 110 326 PMID:26854431