JNJ DGAT2-A 是一种选择性二酰基甘油酰基转移酶 2 (DGAT2) 抑制剂，在表达人 DGAT2 的 Sf9 昆虫细胞膜中的 IC50 值为 0.14 μM。
货号:ajcx27276
CAS:1962931-71-0
分子式:C24H16BrFN4O2S
分子量：523.38
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

DGAT2 inhibitor (IC50 = 140 nM). Exhibits >70-fold selectivity for DGAT2 over DGAT1 and MGAT2.

Qi et al (2012) The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 J.Lipid Res. 53 1106 PMID:22493088 |Irshad et al (2017) Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes. J.Lipid Res. 58 15 PMID:27836993